Formation of P450·P450 complexes and their effect on P450 function
نویسندگان
چکیده
منابع مشابه
Effect of homomeric P450-P450 complexes on P450 function.
Previous studies have shown that the presence of one P450 enzyme can affect the function of another. The goal of the present study was to determine if P450 enzymes are capable of forming homomeric complexes that affect P450 function. To address this problem, the catalytic activities of several P450s were examined in reconstituted systems containing NADPH-POR (cytochrome P450 reductase) and a si...
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ژورنال
عنوان ژورنال: Pharmacology & Therapeutics
سال: 2012
ISSN: 0163-7258
DOI: 10.1016/j.pharmthera.2011.11.009